Hemostatic effect of a chitosan linear polymer (Celox®) in a severe femoral artery bleeding rat model under hypothermia or warfarin therapy
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چکیده
منابع مشابه
Hemostatic effect of a chitosan linear polymer (Celox®) in a severe femoral artery bleeding rat model under hypothermia or warfarin therapy.
BACKGROUND In this study, the hemostatic efficacy of Celox® in rats under hypothermia or warfarin treatment was investigated. METHODS A total of forty-eight Sprague-Dawley female rats weighing 200-350 g were used in the study. Six experimental study groups were designed, as follows: Group 1: Normothermia + compression; Group 2: normothermia + Celox®; Group 3: hypothermia + compression; Group ...
متن کاملassessment of the effect of honey as a topical therapy for intra oral wound healing in rat.
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15 صفحه اولEffect of Combination Therapy Using Hypothermia and Granulocyte Colony-Stimulating Factor in a Rat Transient Middle Cerebral Artery Occlusion Model
Background: Stroke is the third leading cause of death. Hypothermia has been recognized as an effective method in reducing brain injury. In this study, we assessed the effects of granulocyte colony-stimulating factor (G-CSF) as a neuroprotective agent and mild hypothermia on mortality, behavioral function, infarct volume, and brain edema in Wistar rats. Methods: Forty male rats were used in fiv...
متن کاملeffect of combination therapy using hypothermia and granulocyte colony-stimulating factor in a rat transient middle cerebral artery occlusion model
background: stroke is the third leading cause of death. hypothermia has been recognized as an effective method in reducing brain injury. in this study, we assessed the effects of granulocyte colony-stimulating factor (g-csf) as a neuroprotective agent and mild hypothermia on mortality, behavioral function, infarct volume, and brain edema in wistar rats. methods: forty male rats were used in fiv...
متن کاملHemostatic efficacy of local chitosan linear polymer granule in an experimental sheep model with severe bleeding of arteria and vena femoralis.
BACKGROUND The aim of the present study was to evaluate the hemostatic effect of chitosan linear polymer in a sheep model with femoral bleeding. METHODS Following induction of anesthesia and intubation of sheep, groin injury was induced to initiate hemorrhage. Animals were randomly assigned to study and control groups. In the control group, absorbent pads were packed on the wound, and pressur...
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ژورنال
عنوان ژورنال: Turkish Journal of Trauma and Emergency Surgery
سال: 2011
ISSN: 1306-696X,1307-7945
DOI: 10.5505/tjtes.2011.88155